NOTCH3 抗体 (AA 2291-2321)
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Quick Overview for NOTCH3 抗体 (AA 2291-2321) (ABIN3032031)
抗原
See all NOTCH3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2291-2321
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纯化方法
- Purified
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免疫原
- A portion of amino acids 2291-2321 from the human protein was used as the immunogen for this NOTCH3 antibody.
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亚型
- IgG1
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应用备注
- Titration of the NOTCH3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NOTCH3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NOTCH3 (Notch 3 (NOTCH3))
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别名
- NOTCH3
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背景
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq].
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UniProt
- Q9UM47
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途径
- Notch Signaling
抗原
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