MYD88 抗体 (AA 136-164)
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北京 101111
Quick Overview for MYD88 抗体 (AA 136-164) (ABIN3031891)
抗原
See all MYD88 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 136-164
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MyD88 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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别名
- MyD88
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背景
- Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
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UniProt
- Q99836
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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