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MUC1 抗体 (AA 1202-1231)

The 兔 多克隆 anti-MUC1 antibody (ABIN3031860) specifically detects MUC1 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN3031860
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for MUC1 抗体 (AA 1202-1231) (ABIN3031860)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1202-1231

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 1202-1231 from the human protein was used as the immunogen for this MUC1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MUC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    The MUC1 alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. [UniProt]

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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