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MUC1 抗体 (AA 1176-1205)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in IHC, WB 和 ELISA. Suitable for 人.
产品编号 ABIN3031859
发货至: 中国

Quick Overview for MUC1 抗体 (AA 1176-1205) (ABIN3031859)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1176-1205

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 1176-1205 from the human protein was used as the immunogen for this MUC-1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the MUC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MUC-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC-1

    背景

    This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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