MMP14 抗体 (AA 470-499)
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北京 101111
Quick Overview for MMP14 抗体 (AA 470-499) (ABIN3031714)
抗原
See all MMP14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 470-499
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine, Pig, Rabbit
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纯化方法
- Purified
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免疫原
- A portion of amino acids 470-499 from the human protein was used as the immunogen for this MMP14 antibody.
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亚型
- IgM
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应用备注
- Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MMP14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
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别名
- MMP14
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
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UniProt
- P50281
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途径
- Autophagy
抗原
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