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MMP14 抗体 (AA 470-499)

This anti-MMP14 antibody is a 小鼠 单克隆 antibody detecting MMP14 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN3031714
发货至: 中国

Quick Overview for MMP14 抗体 (AA 470-499) (ABIN3031714)

抗原

See all MMP14 抗体
MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

适用

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宿主

  • 78
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小鼠

克隆类型

  • 68
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单克隆

标记

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This MMP14 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

133CT15-10-5-1
  • 抗原表位

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    AA 470-499

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat, Bovine, Pig, Rabbit

    纯化方法

    Purified

    免疫原

    A portion of amino acids 470-499 from the human protein was used as the immunogen for this MMP14 antibody.

    亚型

    IgM
  • 应用备注

    Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000,Immunofluorescence: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MMP14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

    别名

    MMP14

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

    UniProt

    P50281

    途径

    Autophagy
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