MCL-1 抗体 (AA 217-245)
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Quick Overview for MCL-1 抗体 (AA 217-245) (ABIN3031297)
抗原
See all MCL-1 (MCL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 217-245
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 217-245 from the human protein was used as the immunogen for this MCL1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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别名
- MCL1
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背景
- This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
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UniProt
- Q07820
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途径
- MAPK Pathway
抗原
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