LRRK2 抗体 (AA 878-909)
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Quick Overview for LRRK2 抗体 (AA 878-909) (ABIN3031607)
抗原
See all LRRK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 878-909
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 878-909 from the human protein was used as the immunogen for this LRRK2 antibody.
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亚型
- Ig Fraction
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anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibody
LRRK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 2171-2207), (C-Term) antibodyLRRK2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal RB50924 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibodyLRRK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7199 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB07209 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7207 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal 133AT1218 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 133AT720 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 133AT720 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the LRRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LRRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
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别名
- LRRK2
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背景
- Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson's disease identified to date. LRRK2, a genetic mutation, was recently found linked to about 5 percent of inherited cases of Parkinson's disease. By high-resolution recombination mapping and candidate gene sequencing in 46 families, 6 disease-segregating mutations (5 missense and 1 putative splice site mutation). It may be central to the pathogenesis of several major neurodegenerative disorders associated with parkinsonism. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains.
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UniProt
- Q5S007
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
抗原
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