LIM Domain Kinase 1 抗体 (AA 479-508)
Quick Overview for LIM Domain Kinase 1 抗体 (AA 479-508) (ABIN3028800)
抗原
See all LIM Domain Kinase 1 (LIMK1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 479-508
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纯化方法
- Purified
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免疫原
- A portion of amino acids 479-508 from the human protein was used as the immunogen for this LIMK1 antibody.
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亚型
- IgG1 kappa
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应用备注
- Titration of the LIMK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LIMK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LIM Domain Kinase 1 (LIMK1)
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别名
- LIMK1
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背景
- Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
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UniProt
- P53667
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途径
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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