JAK2 抗体 (AA 1101-1132)
Quick Overview for JAK2 抗体 (AA 1101-1132) (ABIN3031513)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1101-1132
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纯化方法
- Purified
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免疫原
- A portion of amino acids 1101-1132 from the human protein was used as the immunogen for this JAK2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the JAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the JAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- JAK2 (Janus Kinase 2 (JAK2))
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别名
- JAK2
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背景
- This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
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UniProt
- O60674
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
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