ISG15 抗体 (AA 31-61)
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北京 101111
Quick Overview for ISG15 抗体 (AA 31-61) (ABIN3031502)
抗原
See all ISG15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-61
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 31-61 from the human protein was used as the immunogen for this ISG15 antibody.
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亚型
- Ig Fraction
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anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-165) antibody
ISG15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-165) antibodyISG15 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (Middle Region) antibodyISG15 适用: 人, 兔, Cow, 犬, 马, Pig, 绵羊, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 31-61), (N-Term) antibodyISG15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02791 unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 39-68), (N-Term) antibodyISG15 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) antibodyISG15 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (C-Term) antibodyISG15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 80-129) antibodyISG15 适用: 人, 兔, Cow, 犬, 马, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 2-157) antibodyISG15 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-157) antibodyISG15 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3E5 unconjugated
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应用备注
- Titration of the ISG15 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ISG15 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ISG15 (ISG15 Ubiquitin-Like Modifier (ISG15))
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别名
- ISG15
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背景
- ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , but not IFN-gamma . ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression. Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta. ISG15 has has also been shown to function intracellularly as a ubiquitin homolog.
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UniProt
- P05161
抗原
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