Integrin beta 2 抗体
Quick Overview for Integrin beta 2 抗体 (ABIN3031375)
抗原
See all Integrin beta 2 (ITGB2) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- This Integrin beta 2 antibody was produced from rabbits immunized with a recombinant protein from the human ITGB2.
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亚型
- Ig Fraction
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应用备注
- Titration of the Integrin beta 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Integrin beta 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Integrin beta 2 (ITGB2)
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别名
- Integrin beta 2
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背景
- The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
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UniProt
- P05107
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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