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INSRR 抗体 (AA 16-47)

This anti-INSRR antibody is a 兔 多克隆 antibody detecting INSRR in WB, ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN3029806
发货至: 中国

Quick Overview for INSRR 抗体 (AA 16-47) (ABIN3029806)

抗原

See all INSRR 抗体
INSRR (Insulin Receptor-Related Receptor (INSRR))

适用

  • 52
  • 23
  • 8
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 57
  • 1

克隆类型

  • 55
  • 3
多克隆

标记

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  • 5
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  • 5
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This INSRR antibody is un-conjugated

应用范围

  • 39
  • 34
  • 20
  • 14
  • 13
  • 8
  • 5
  • 5
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
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    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 16-47

    纯化方法

    Purified

    免疫原

    A portion of amino acids 16-47 from the human protein was used as the immunogen for this Insulin receptor-related antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Insulin receptor-related antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Insulin receptor-related antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    INSRR (Insulin Receptor-Related Receptor (INSRR))

    别名

    Insulin Receptor-Related

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

    UniProt

    P14616

    途径

    RTK signaling
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