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Insulin Receptor 抗体 (AA 21-52)

This anti-Insulin Receptor antibody is a 兔 多克隆 antibody detecting Insulin Receptor in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN3031335
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (AA 21-52) (ABIN3031335)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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宿主

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克隆类型

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  • 48
多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 21-52

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat

    纯化方法

    Purified

    免疫原

    A portion of amino acids 21-52 from the human protein was used as the immunogen for this Insulin Receptor antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Insulin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Insulin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Insulin Receptor (INSR)

    别名

    Insulin Receptor

    背景

    INSR binds insulin and has a tyrosine-protein kinase activity. Autophosphorylation activates the kinase activity. This Type I mebrane protein is composed of a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. After being transported from the endoplasmic reticulum to the Golgi apparatus, the single glycosylated precursor is further glycosylated and then cleaved, followed by its transport to the plasma membrane.

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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