IL12 抗体 (AA 168-195)
Quick Overview for IL12 抗体 (AA 168-195) (ABIN3031445)
抗原
See all IL12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 168-195
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 168-195 from the human protein was used as the immunogen for this IL-12 antibody.
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亚型
- Ig Fraction
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anti-Interleukin 12 (IL12) (AA 51-150) antibody
IL12 适用: 人 ELISA, WB, IF (p), IF (cc), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 (IL12) antibodyIL12 适用: 小鼠 ELISA, WB, Neut 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 (IL12) antibodyIL12 适用: 人 ELISA, WB, Neut 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Titration of the IL-12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL12 (Interleukin 12 (IL12))
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别名
- IL-12
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背景
- IL12A is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
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UniProt
- P29459
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途径
- JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
抗原
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