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ERBB3 抗体 (AA 24-55)

This anti-ERBB3 antibody is a 兔 多克隆 antibody detecting ERBB3 in WB, IHC, ELISA 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN3029524
发货至: 中国

Quick Overview for ERBB3 抗体 (AA 24-55) (ABIN3029524)

抗原

See all ERBB3 抗体
ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ERBB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 24-55

    纯化方法

    Purified

    免疫原

    A portion of amino acids 24-55 from the human protein was used as the immunogen for this HER3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the HER3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the HER3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

    别名

    HER3

    背景

    HER3/ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins and NTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This protein is predominantly expressed in epithelial tissues and brain. The cytoplasmic part of the receptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote its association with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressed in a subset of human mammary tumors.

    UniProt

    P21860

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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