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FKBP1A 抗体 (AA 43-74)

This anti-FKBP1A antibody is a 兔 多克隆 antibody detecting FKBP1A in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN3030968
发货至: 中国

Quick Overview for FKBP1A 抗体 (AA 43-74) (ABIN3030968)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

  • 64
  • 29
  • 22
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 64
  • 9

克隆类型

  • 55
  • 18
多克隆

标记

  • 35
  • 10
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This FKBP1A antibody is un-conjugated

应用范围

  • 43
  • 29
  • 18
  • 16
  • 10
  • 8
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 11
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 43-74

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat, Bovine, Rabbit

    纯化方法

    Purified

    免疫原

    A portion of amino acids 43-74 from the human protein was used as the immunogen for this FKBP12 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the FKBP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FKBP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKBP12

    背景

    FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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