MAPK7 抗体 (AA 527-557)
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Quick Overview for MAPK7 抗体 (AA 527-557) (ABIN3031833)
抗原
See all MAPK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 527-557
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纯化方法
- Purified
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免疫原
- A portion of amino acids 527-557 from the human protein was used as the immunogen for this ERK4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ERK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ERK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
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别名
- ERK4
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背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
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UniProt
- P31152
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
抗原
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