EGFR 抗体 (AA 1070-1099)
Quick Overview for EGFR 抗体 (AA 1070-1099) (ABIN3030849)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1070-1099
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1070-1099 from the human protein was used as the immunogen for this Epidermal Growth Factor Receptor antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Epidermal Growth Factor Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Epidermal Growth Factor Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- Epidermal Growth Factor Receptor
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背景
- The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
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UniProt
- P00533
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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