EPH Receptor A2 抗体 (AA 518-552)
Our Local Distributor
北京 101111
Quick Overview for EPH Receptor A2 抗体 (AA 518-552) (ABIN3030815)
抗原
See all EPH Receptor A2 (EPHA2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 518-552
-
交叉反应 （详细）
- Expected species reactivity: Primate
-
纯化方法
- Antigen affinity purified
-
免疫原
- This EPHA2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 518-552 amino acids from the central region of human EPHA2.
-
亚型
- Ig Fraction
-
-
anti-EPH Receptor A2 (EPHA2) (AA 30-60), (N-Term) antibody
EPHA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01579 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 901-976) antibodyEPHA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 204-326) antibodyEPHA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 适用: 人 FACS, IF, cELISA 宿主: 小鼠 Monoclonal Kalpha-5H5 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 30-60) antibodyEPHA2 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 333-347), (Extracellular) antibodyEPHA2 适用: 人 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 847-976) antibodyEPHA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (Tyr588), (Tyr596) antibodyEPHA2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibodyEPHA2 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1B3C7 unconjugated
-
-
应用备注
- Titration of the EPHA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the EPHA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- EPH Receptor A2 (EPHA2)
-
别名
- EPHA2
-
背景
- Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand- independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
-
UniProt
- P29317
-
途径
- RTK signaling
抗原
-
