EPH Receptor A2 抗体 (AA 296-323)
Quick Overview for EPH Receptor A2 抗体 (AA 296-323) (ABIN3030814)
抗原
See all EPH Receptor A2 (EPHA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 296-323
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 296-323 from the mouse protein was used as the immunogen for this Epha2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Epha2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Epha2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EPH Receptor A2 (EPHA2)
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别名
- Epha2
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背景
- Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell interactions guiding early hindbrain development.
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UniProt
- Q03145
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途径
- RTK signaling
抗原
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