DDR2 抗体
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北京 101111
Quick Overview for DDR2 抗体 (ABIN3030741)
抗原
See all DDR2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- This DDR2 antibody was produced from rabbits immunized with a his tag recombinant protein of human DDR2/TYRO10.
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亚型
- Ig Fraction
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anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibody
DDR2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B11E4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 245-350) antibodyDDR2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 578-817) antibodyDDR2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 447-540) antibodyDDR2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (C-Term) antibodyKO Validated DDR2 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17713 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyKD Validated DDR2 适用: 人 WB 宿主: 兔 Monoclonal 25GB2210 unconjugated Recombinant Antibody
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 816-843) antibodyDDR2 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 290-400) antibodyDDR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DDR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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别名
- DDR2 (TYRO10)
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背景
- DDR2/TYRO10 is a tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. [UniProt]
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UniProt
- Q16832
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途径
- RTK signaling
抗原
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