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Cyclin D3 抗体 (AA 33-66)

CCND3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030599
发货至: 中国
  • 抗原 See all Cyclin D3 (CCND3) 抗体
    Cyclin D3 (CCND3)
    抗原表位
    • 33
    • 16
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-66
    适用
    • 107
    • 44
    • 33
    • 16
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 94
    • 15
    克隆类型
    • 86
    • 23
    多克隆
    标记
    • 49
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Cyclin D3 antibody is un-conjugated
    应用范围
    • 79
    • 33
    • 28
    • 27
    • 26
    • 19
    • 15
    • 15
    • 10
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    This Cyclin D3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 33-66 amino acids from the N-terminal region of rat Ccnd3.
    亚型
    Ig Fraction
    Top Product
    Discover our top product CCND3 Primary Antibody
  • 应用备注
    Titration of the Cyclin D3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the Cyclin D3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    Cyclin D3 (CCND3)
    Abstract
    CCND3 产品
    别名
    zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
    背景
    Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
    UniProt
    P48961
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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