Cyclin D3 抗体 (AA 33-66)
Quick Overview for Cyclin D3 抗体 (AA 33-66) (ABIN3030599)
抗原
See all Cyclin D3 (CCND3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 33-66
-
纯化方法
- Antigen affinity purified
-
免疫原
- This Cyclin D3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 33-66 amino acids from the N-terminal region of rat Ccnd3.
-
亚型
- Ig Fraction
-
-
anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (pThr283) antibodyCCND3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 136-292) antibodyCCND3 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 121-220) antibodyCCND3 适用: 人, 兔 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) antibodyCCND3 适用: 人 WB, IF (cc) 宿主: 兔 Monoclonal 4A8 unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Titration of the Cyclin D3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the Cyclin D3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- Cyclin D3 (CCND3)
-
背景
- Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
-
UniProt
- P48961
-
途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
抗原
-
