Cyclin A 抗体 (AA 358-389)
Quick Overview for Cyclin A 抗体 (AA 358-389) (ABIN3030582)
抗原
See all Cyclin A (CCNA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 358-389
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纯化方法
- Purified
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免疫原
- A portion of amino acids 358-389 from the human protein was used as the immunogen for this Cyclin A2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Cyclin A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Cyclin A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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背景
- CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
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UniProt
- P20248
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途径
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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