CSF1R 抗体 (AA 940-971)
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Quick Overview for CSF1R 抗体 (AA 940-971) (ABIN3030557)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 940-971
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纯化方法
- Purified
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免疫原
- A portion of amino acids 940-971 from the human protein was used as the immunogen for this CSF1R antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CSF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CSF1R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CSF1R
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背景
- CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. This protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.
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UniProt
- P07333
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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