CREB1 抗体 (AA 105-132)
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Quick Overview for CREB1 抗体 (AA 105-132) (ABIN3030270)
抗原
See all CREB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 105-132
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 105-132 from the human protein was used as the immunogen for this CREB antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CREB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CREB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
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别名
- CREB
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背景
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
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UniProt
- P16220
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
抗原
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