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CCR5 抗体 (AA 151-177)

This anti-CCR5 antibody is a 兔 多克隆 antibody detecting CCR5 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3030217
发货至: 中国

Quick Overview for CCR5 抗体 (AA 151-177) (ABIN3030217)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

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宿主

  • 107
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克隆类型

  • 105
  • 50
  • 4
多克隆

标记

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This CCR5 antibody is un-conjugated

应用范围

  • 91
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  • 11
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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 151-177

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 151-177 from the human protein was used as the immunogen for this CCR5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the CCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CCR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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