CCR3 抗体 (AA 291-318)
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Quick Overview for CCR3 抗体 (AA 291-318) (ABIN3030491)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 291-318
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 291-318 from the human protein was used as the immunogen for this CCR3 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CCR3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
- CCR3
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背景
- CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
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UniProt
- P51677
抗原
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