Caspase 12 抗体 (AA 165-193)
Quick Overview for Caspase 12 抗体 (AA 165-193) (ABIN3030291)
抗原
See all Caspase 12 (CASP12) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 165-193
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 165-193 from the human protein was used as the immunogen for this Caspase-12 antibody.
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亚型
- Ig Fraction
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anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 201-300) antibody
CASP12 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-413) antibodyCASP12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-244) antibodyCASP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 71-84) antibodyCASP12 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 61-282) antibodyCASP12 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 100-116) antibodyCASP12 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-100) antibodyCASP12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193) antibodyCASP12 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB31705 unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 95-318), (N-Term) antibodyCASP12 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p) 宿主: 大鼠 Monoclonal 14F7 unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 172-201), (Middle Region) antibodyCASP12 适用: 人 WB, FACS, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the Caspase-12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Caspase-12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
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别名
- Caspase-12
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背景
- Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
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UniProt
- Q6UXS9
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途径
- Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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