BMI1 抗体 (AA 230-265)
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北京 101111
Quick Overview for BMI1 抗体 (AA 230-265) (ABIN3030166)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-265
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纯化方法
- Antigen affinity purified
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免疫原
- This BMI1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 230-265 amino acids from the C-terminal region of human BMI1.
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亚型
- Ig Fraction
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应用备注
- Titration of the BMI1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BMI1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- BMI1
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背景
- Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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