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Beclin 1 抗体 (AA 210-239)

This anti-Beclin 1 antibody is a 兔 多克隆 antibody detecting Beclin 1 in WB, ELISA, IHC 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN3030156
发货至: 中国

Quick Overview for Beclin 1 抗体 (AA 210-239) (ABIN3030156)

抗原

See all Beclin 1 (BECN1) 抗体
Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Beclin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 210-239

    交叉反应 (详细)

    Expected species reactivity: Bovine, Pig, Rat

    纯化方法

    Purified

    免疫原

    A portion of amino acids 210-239 from the human protein was used as the immunogen for this Beclin antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Beclin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Beclin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

    别名

    Beclin 1

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.

    UniProt

    Q14457

    途径

    Autophagy
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