ASCL1 抗体 (AA 63-90)
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Quick Overview for ASCL1 抗体 (AA 63-90) (ABIN3029829)
抗原
See all ASCL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-90
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ASCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ASCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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别名
- ASCL1 (MASH1)
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背景
- This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
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UniProt
- P50553
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途径
- Dopaminergic Neurogenesis
抗原
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