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APC 抗体 (AA 1148-1176)
APC
适用: 小鼠
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
APC抗体详情
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抗原
See all APC 抗体
APC
(Adenomatous Polyposis Coli (APC))
抗原表位
All epitopes for APC 抗体
AA 1148-1176
适用
All reactivities for APC 抗体
小鼠
宿主
All hosts for APC 抗体
兔
克隆类型
All clonalities for APC 抗体
多克隆
标记
All conjugates for APC 抗体
This APC antibody is un-conjugated
应用范围
All applications for APC 抗体
Western Blotting (WB), ELISA
纯化方法
Antigen affinity purified
免疫原
A portion of amino acids 1148-1176 from the human protein was used as the immunogen for this APC antibody.
亚型
Ig Fraction
Top Product
Discover our top product APC Primary Antibody
Alternatives
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使用细节
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应用备注
Titration of the APC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the APC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
APC目标详情
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抗原
APC
(Adenomatous Polyposis Coli (APC))
别名
APC (APC 产品 )
别名
dp2 antibody, dp3 antibody, fap antibody, fpc antibody, xapc antibody, dp2.5 antibody, AI047805 antibody, AU020952 antibody, AW124434 antibody, CC1 antibody, Min antibody, mAPC antibody, BTPS2 antibody, DP2 antibody, DP2.5 antibody, DP3 antibody, GS antibody, PPP1R46 antibody, RATAPC antibody, APC1 antibody, APC, WNT signaling pathway regulator antibody, adenomatous polyposis coli antibody, adenomatous polyposis coli protein, putative antibody, adenomatosis polyposis coli antibody, adenomatous polyposis coli L homeolog antibody, APC antibody, apc antibody, Smp_139190 antibody, Apc antibody, apc.L antibody
背景
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
UniProt
P25054
途径
WNT signaling , Stem Cell Maintenance , Cell-Cell Junction Organization
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