TLR2 抗体 (AA 720-749)
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Quick Overview for TLR2 抗体 (AA 720-749) (ABIN3029165)
抗原
See all TLR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 720-749
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纯化方法
- Purified
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免疫原
- A portion of amino acids 720-749 from the mouse protein was used as the immunogen for this anti-TLR2 antibody.
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亚型
- Ig Fraction
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anti-Toll-Like Receptor 2 (TLR2) (AA 212-242) antibody
TLR2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 2 (TLR2) antibodyTLR2 适用: 人 WB 宿主: 小鼠 Monoclonal 1070CT4-2-3-2 unconjugated
anti-Toll-Like Receptor 2 (TLR2) (AA 281-310) antibodyTLR2 适用: 人 WB 宿主: 兔 Polyclonal RB33608 unconjugated
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应用备注
- Titration of the anti-TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the anti-TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TLR2 (Toll-Like Receptor 2 (TLR2))
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别名
- TLR2
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背景
- TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
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UniProt
- Q9QUN7
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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