EGFR 抗体 (AA 1004-1033)
Quick Overview for EGFR 抗体 (AA 1004-1033) (ABIN3030837)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1004-1033
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 1004-1033 from the human protein was used as the immunogen for this anti-EGFR antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the anti-EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the anti-EGFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
别名
- EGFR
-
背景
- The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
-
UniProt
- P00533
-
途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
-