EGF 抗体 (AA 940-967)
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Quick Overview for EGF 抗体 (AA 940-967) (ABIN3030833)
抗原
See all EGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 940-967
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 940-967 from the human protein was used as the immunogen for this anti-EGF antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the anti-EGF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the anti-EGF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EGF (Epidermal Growth Factor (EGF))
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别名
- EGF
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背景
- This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
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UniProt
- P01133
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
抗原
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