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ADAM17 抗体 (AA 195-224)

The 兔 多克隆 anti-ADAM17 antibody is suitable to detect ADAM17 in samples from 人. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN3029858
发货至: 中国
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Quick Overview for ADAM17 抗体 (AA 195-224) (ABIN3029858)

抗原

See all ADAM17 抗体
ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADAM17 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 195-224

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 195-224 from the human protein was used as the immunogen for this ADAM17 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the ADAM17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ADAM17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

    别名

    ADAM17

    背景

    ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

    UniProt

    P78536

    途径

    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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