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ADAM17 抗体 (AA 794-823)
ADAM17
适用: 人
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
ADAM17抗体详情
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抗原
See all ADAM17 抗体
ADAM17
(ADAM Metallopeptidase Domain 17 (ADAM17))
抗原表位
All epitopes for ADAM17 抗体
AA 794-823
适用
All reactivities for ADAM17 抗体
人
宿主
All hosts for ADAM17 抗体
兔
克隆类型
All clonalities for ADAM17 抗体
多克隆
标记
All conjugates for ADAM17 抗体
This ADAM17 antibody is un-conjugated
应用范围
All applications for ADAM17 抗体
Western Blotting (WB), ELISA
纯化方法
Antigen affinity purified
免疫原
A portion of amino acids 794-823 from the human protein was used as the immunogen for this ADAM17 antibody.
亚型
Ig Fraction
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Discover our top product ADAM17 Primary Antibody
Alternatives
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使用细节
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应用备注
Titration of the ADAM17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the ADAM17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
ADAM17目标详情
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抗原
ADAM17
(ADAM Metallopeptidase Domain 17 (ADAM17))
别名
ADAM17 (ADAM17 产品 )
别名
ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
背景
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2. [UniProt]
UniProt
P78536
途径
Notch Signaling , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Response to Growth Hormone Stimulus
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