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ADAM17 抗体 (AA 794-823)

ADAM17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029859
发货至: 中国
  • 抗原 See all ADAM17 抗体
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    抗原表位
    • 16
    • 13
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 794-823
    适用
    • 108
    • 54
    • 52
    • 4
    • 4
    • 4
    • 1
    • 1
    宿主
    • 93
    • 13
    • 2
    • 1
    • 1
    克隆类型
    • 86
    • 24
    多克隆
    标记
    • 52
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM17 antibody is un-conjugated
    应用范围
    • 80
    • 47
    • 39
    • 15
    • 14
    • 14
    • 11
    • 11
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 794-823 from the human protein was used as the immunogen for this ADAM17 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ADAM17 Primary Antibody
  • 应用备注
    Titration of the ADAM17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the ADAM17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    别名
    ADAM17 (ADAM17 产品)
    别名
    ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
    背景
    Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2. [UniProt]
    UniProt
    P78536
    途径
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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