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SIRT1 抗体 (AA 566-601)

Name: SIRT1 抗体 (AA 566-601)
SKU: ABIN3032583
Availability: OutOfStock

This anti-SIRT1 antibody is a 兔多克隆 antibody detecting SIRT1 in WB, IHC, ELISA 和 IF. Suitable for 人和小鼠.

Western blot analysis of lysate from mouse F9 cell line using SIRT1 antibody at 1:1000. (SIRT1 抗体 (AA 566-601))

IHC analysis of FFPE mouse brain section using SIRT1 antibody at 1:25. (SIRT1 抗体 (AA 566-601))

IHC

Fluorescent image of A549 cells stained with SIRT1 antibody. (SIRT1 抗体 (AA 566-601))

IHC

5 images

产品编号 ABIN3032583

发货至: 中国

Quick Overview for SIRT1 抗体 (AA 566-601) (ABIN3032583)

抗原

See all SIRT1 抗体

SIRT1 (Sirtuin 1 (SIRT1))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This SIRT1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Discover our top product SIRT1 Primary Antibody

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AA 566-601

纯化方法

Antigen affinity purified

免疫原

A portion of amino acids 566-601 of the mouse protein was used as the immunogen for the SIRT1 antibody.

亚型

Ig Fraction
anti-Sirtuin 1 (SIRT1) (AA 101-200) antibody
SIRT1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 456-555) antibody
SIRT1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 7B7 unconjugated

anti-Sirtuin 1 (SIRT1) (AA 448-747) antibody
SIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 566-601), (C-Term) antibody
SIRT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB50965 unconjugated

anti-Sirtuin 1 (SIRT1) antibody
SIRT1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F3 unconjugated

anti-Sirtuin 1 (SIRT1) antibody
KO Validated SIRT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (N-Term) antibody
SIRT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 456-555) antibody
SIRT1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 7B7 unconjugated

anti-Sirtuin 1 (SIRT1) (pSer47) antibody
SIRT1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 244-498) antibody
SIRT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

The stated application concentrations are suggested starting points. Titration of the SIRT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Immunofluorescence: 1:25,Western blot: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS pH 7.4 with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at 4°C for up to one month. For long term, aliquot the SIRT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

SIRT1 (Sirtuin 1 (SIRT1))

别名

SIRT1

背景

SIRT1 is a NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. [UniProt]

UniProt

Q923E4

途径

MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling