The stated application concentrations are suggested starting points. Titration of the FADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable
限制
仅限研究用
缓冲液
Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
储存条件
-20 °C
储存方法
Store the FADD antibody at -20°C.
抗原
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
别名
FADD
背景
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]