PINK1 抗体 (AA 118-147)
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北京 101111
Quick Overview for PINK1 抗体 (AA 118-147) (ABIN3032405)
抗原
See all PINK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-147
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纯化方法
- Purified
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免疫原
- A portion of amino acids 118-147 from the human protein was used as the immunogen for this PINK1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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别名
- PINK1
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背景
- Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
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UniProt
- Q9BXM7
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途径
- Autophagy
抗原
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