YBX1 抗体
Quick Overview for YBX1 抗体 (ABIN4953124)
抗原
See all YBX1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity
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免疫原
- Amino acids ENPKPQDGKETKAADPPAENSSAPEAEQ of human YB1 were used as the immunogen for the YB1 antibody.
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亚型
- IgG
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anti-Y Box Binding Protein 1 (YBX1) (AA 100-200) antibody
YBX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 100-200) antibodyYBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 293-320), (C-Term) antibodyYBX1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 51-139) antibodyYBX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal YBX1-2430 unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人, 大鼠, 小鼠, Cow, 犬, 小鸡, Pig WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (pSer102) antibodyYBX1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rYBX1-2430 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the YB1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the YB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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别名
- YB1
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背景
- YBX1 (Y box binding protein 1), commonly referred to as YB-1 by researchers, is a human protein. YB1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a molecular mass of 35,414 and contains 18 % basic residues and putative nuclear localization signals. The YBX1 gene is mapped on 1p34.2. Ybx1 was highly expressed in mouse erythroid myeloid lymphoid clone-1 (EML), a hematopoietic precursor cell line, but that it was downregulated in myeloid progenitors and in Gmcsf-treated EML cells during myeloid differentiation. Ybx1 was expressed at high levels in myeloid leukemic cells at different developmental stages. Knockdown of YBX1 in a human leukemic cell line inhibited proliferation ability, induced apoptosis, and induced megakaryocytic differentiation in response to arsenic trioxide treatment. YBX1 is downregulated during myeloid differentiation and aberrant YBX1 expression in leukemic cells may contribute to leukemia development by blocking differentiation.
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UniProt
- P67809
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途径
- Regulation of Muscle Cell Differentiation
抗原
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