L-Selectin 抗体 (AA 39-372)
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Quick Overview for L-Selectin 抗体 (AA 39-372) (ABIN4950499)
抗原
See all L-Selectin (SELL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-372
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 39-372 of human CD62L were used as the immunogen for the CD62L antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CD62L antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA : 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CD62L antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- L-Selectin (SELL) (Selectin L (SELL))
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别名
- L-Selectin (CD62L)
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背景
- CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
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UniProt
- P14151
抗原
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