NADPH Oxidase 4 抗体
Quick Overview for NADPH Oxidase 4 抗体 (ABIN4949834)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Protein G affinity chromatography
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免疫原
 - Human recombinant protein was used as the immunogen for this NOX4 antibody.
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亚型
 - IgG2b kappa
 
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应用备注
 - Titering of the NOX4 antibody may be required for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,ELISA: suitable, order BSA-free formulation for coating,WB: 0.5-1 μg/mL
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
 - Azide free
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store the NOX4 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
 
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- NADPH Oxidase 4 (NOX4)
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别名
 - NOX4
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背景
 - The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
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基因ID
 - 4821
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途径
 - Carbohydrate Homeostasis, Smooth Muscle Cell Migration
 
抗原
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