JUP 抗体 (N-Term)
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北京 101111
Quick Overview for JUP 抗体 (N-Term) (ABIN4949714)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full length human gamma Catenin fused to maltose binding protein was used as the immunogen for the Plakoglobin antibody. The epitope has been found to be in the N-terminal region.
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亚型
- IgG1 kappa
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anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-745) antibodyJUP 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyVerified JUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 556-745) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-300) antibodyJUP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Cat WB, IF, FACS 宿主: 小鼠 Monoclonal 15F11 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal CTNG-1664 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1-10E05 unconjugated
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应用备注
- Titration of the Plakoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL,Immunoprecipitation: suitable
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Plakoglobin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- JUP (Junction Plakoglobin (JUP))
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别名
- Gamma Catenin / Plakoglobin
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背景
- It recognizes a protein of 80-87 kDa, identified as gamma-Catenin or Plakoglobin. The catenins (alpha, beta, gamma and δ,) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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