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CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN4949564
发货至: 中国

Quick Overview for CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) 抗体 (ABIN4949564)

抗原

CFTR / Cystic Fibrosis Transmembrane Regulator

适用

  • 9
  • 4

宿主

  • 5
  • 4
小鼠

克隆类型

  • 9
单克隆

标记

  • 9
非结合性

应用范围

  • 9
  • 7
  • 4
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

CFTR-1643
  • 抗原表位

    AA 258-385

    纯化方法

    Protein G affinity chromatography

    免疫原

    A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.

    亚型

    IgG2b
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. IF: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CFTR / Cystic Fibrosis Transmembrane Regulator

    背景

    Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]

    基因ID

    1080
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