CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) 抗体
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Quick Overview for CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) 抗体 (ABIN4949564)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 258-385
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纯化方法
- Protein G affinity chromatography
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免疫原
- A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
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亚型
- IgG2b
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. IF: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CFTR / Cystic Fibrosis Transmembrane Regulator
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背景
- Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
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基因ID
- 1080
抗原
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