CFTR / Cystic Fibrosis Transmembrane Regulator 抗体
Quick Overview for CFTR / Cystic Fibrosis Transmembrane Regulator 抗体 (ABIN4949562)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human recombinant protein was used as the immunogen for this CFTR antibody.
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亚型
- IgG1
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anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody
适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人 IHC (p), IF, WB 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p), IF, WB 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p), IF, WB 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. Immunofluorescence: 1-2 μg/mL,Western blot: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CFTR / Cystic Fibrosis Transmembrane Regulator
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背景
- Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
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基因ID
- 1080
抗原
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