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Calnexin 抗体

This anti-Calnexin antibody (ABIN4949485) is a Mouse Monoclonal antibody detecting Calnexin in WB, ELISA, IHC (p), IF/ICC. Suitable for Human.
产品编号 ABIN4949485
发货至: 中国

Quick Overview for Calnexin 抗体 (ABIN4949485)

抗原

See all Calnexin (CANX) 抗体
Calnexin (CANX)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Calnexin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC)

克隆位点

CANX-1541
  • 无交叉反应

    大鼠

    纯化方法

    Protein G affinity chromatography

    免疫原

    A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Titering of the Calnexin antibody may be required for optimal performance.\. ELISA: 2-4 μg/mL (order BSA-free format for coating),WB: 1-2 μg/mL,IF/ICC: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Calnexin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    Calnexin (CANX)

    别名

    Calnexin

    背景

    It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

    途径

    MAPK Pathway, Thyroid Hormone Synthesis
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