Optimal dilution of the AMACR antibody should be determined by the researcher.\. Immunohistology (FFPE): 1-2 μg/mL for 30 minutes at RT,IF: 1-2 μg/mL
限制
仅限研究用
浓度
1 mg/mL
缓冲液
1 mg/mL in sterile PBS, BSA free, sodium azide free
储存液
Azide free
储存条件
4 °C,-20 °C
储存方法
Store the AMACR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
抗原
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
别名
AMACR / p504S
背景
AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.