Complement Factor H 抗体
Quick Overview for Complement Factor H 抗体 (ABIN492503)
抗原
See all Complement Factor H (CFH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Clone OX-24 inhibits the binding of factor H to surface bound C3. This antibody recognizes the Human serum complement protein factor H and a 43-49 kDa truncated form of factor H.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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产品特性
- Synonyms: CFH, HF, HF1, HF2, H factor 1
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纯化方法
- Protein G Chromatography.
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免疫原
- Purified Human complement factor H protein
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亚型
- IgG1
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应用备注
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ELISA. Western blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry on Paraffin Sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Complement Factor H (CFH)
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背景
- Factor H (CFH) is a protein with twenty short consensus repeat (SCR) domains. Factor H is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in Factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2
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基因ID
- 3075
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UniProt
- P08603
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途径
- Complement System, Cellular Response to Molecule of Bacterial Origin
抗原
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